Red cell storage and prognosis
نویسندگان
چکیده
منابع مشابه
Red blood cell storage lesion.
The past two decades have witnessed increased scrutiny regarding efficacy and risk of the once unquestioned therapy of red blood cell (RBC) transfusion. Simultaneously, a variety of changes have been identified within the RBC and storage media during RBC preservation that are correlated with reduced tissue oxygenation and transfusion-associated adverse effects. These alterations are collectivel...
متن کاملClinical effects of red blood cell storage.
BACKGROUND Well-characterized biochemical, structural, and physiological changes occur when red blood cells (RBCs) are stored for a period of time and are collectively called the storage lesion. METHODS Key study results are summarized and contrasted and new data from recently completed randomized controlled trials will be discussed. RESULTS It is unclear whether in vitro changes to RBCs th...
متن کاملRed cell storage: does duration matter?
The report by Solomon et al in this issue of Blood is a welcome addition to understanding the clinical impact of prolonged red cell storage.
متن کاملTransbilayer mobility and distribution of red cell phospholipids during storage.
We studied phospholipid topology and transbilayer mobility in red cells during blood storage. The distribution of phospholipids was determined by measuring the reactivity of phosphatidylethanolamine with fluorescamine and the degradation of phospholipids by phospholipase A2 and sphingomyelinase C. Phospholipid mobility was measured by determining transbilayer movements of spin-labeled phospholi...
متن کاملRed Blood Cell Concentrate Storage and Survival After Cardiac Surgery.
Methods |We identified all patients who underwent coronary artery bypass graft surgery, heart valve surgery, or both between 1997 and 2012 from the SWEDEHEART register, which records informationonpatientswhoundergoheart surgery in Sweden.3 Transfusion data were obtained from the SCANDAT2 database, a nationwide register of blood transfusions.4 Linkagewithnational health data registers providedvi...
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ژورنال
عنوان ژورنال: Vox Sanguinis
سال: 2010
ISSN: 0042-9007
DOI: 10.1111/j.1423-0410.2010.01441.x